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One retrospective observational study conducted in Japan has suggested that the early administration of this compound was associated with better functional outcomes and reduce HT after AIS (245), although there is data suggesting that the use of this compound may be related to increased HT (246)

Most documented protocols treat glutathione supplementation as a maintenance intervention rather than a cycled compound

Furthermore, the binding of ABHD5 to PLIN1 (138) and binding of G0S2 to PNPLA2 prevents their ubiquitination and degradation by the proteasome (133)

Its versatility makes it a key tool in preclinical studies investigating tissue recovery and structural health