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But if your B12 is high without supplementation , it can be a marker for underlying conditions that require medical evaluation, including liver disease, kidney dysfunction, and certain cancers

B12 works to metabolize homocysteine, an amino acid that at elevated levels is a well-established independent risk factor for heart disease and stroke

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It exhibits an IC 50 of approximately 1 M for NNMT inhibition 4 , with favorable pharmacokinetic properties

Other reported effects include: Headaches and dizziness Nausea and gastrointestinal discomfort Allergic reactions to B12 formulations (rare) If you experience symptoms suggesting a severe allergic reaction (difficulty breathing, severe rash, swelling of face/throat), seek emergency medical attention immediately by calling 999 or attending A&E