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[7] [2] By 1986, the major review of the field by Graf and Kastin concluded that the various physiological functions of DSIP and its mechanism of action remain to be established. [2] That sentence was written four decades ago and has not been superseded

Peptides such as AOD-9604 have been developed to explore signalling pathways and receptor interactions in controlled laboratory environments

For example, a tendon fibroblast model study reported changes in tendon fibroblast outgrowth, cell survival under stress conditions, and cell migration, with discussion of FAK-paxillin pathway involvement [4]