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The observation that paracrine signaling in WNT-medulloblastoma was associated with fenestrated tumor vessels that lack ABC transporters suggests that brain tumor vessels can indeed be modulated to allow a better penetration of drugs [117]

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Therefore, the inclusion of patients with hyperuricemia can complicate the association between UA levels and cognitive function

Prog Brain Res

At physiological concentrations, ROS is important to cellular division, but excessive ROS leads to stressed damages to protein, DNA and lipid (Szczepanowska et al., 2012

Vitamin D and the Pathophysiology of Inflammatory Skin Diseases