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So while acetylcholine normally provides the just the right amount of alertness when it b inds to its receptors, nicotine produces a much more intense response (increased alertness, pleasurable feelings) due to its higher concentrations at the acetylcholine receptors

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We wanted to determine if completely or partially substituting e-cigarettes for cigarettes would be beneficial for persons concerned about respiratory symptoms. - James Sargent, MD We were interested in knowing, for people that didnt have symptoms, what was the risk of developing symptoms at follow-up across the four groups? he explains

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