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However, seek medical care immediately if you experience: Chest pain Severe shortness of breath Fainting Confusion Severe anxiety or panic that feels unmanageable For people quitting heavy smoking, drinking, or multiple substances at once, medical supervision may be recommended

In the US, where it is the leading cause of preventable death, smoking kills 480,000 people each year and shortens the life of an average user by 10 years

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Our research helps to tell us why, paving the way for improved prevention and treatment

This is part of a broader effort to reduce smoking rates in these countries, which have high smoking rates and significant public health concerns