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"US adult smoking rate looks unchanged, vaping rate higher"

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Similarly, 4-aminobiphenyl, metabolized by hepatic CYP1A2, produces reactive intermediates that form DNA adducts in hepatocytes, increasing the mutational burden [27]

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The study also analyzed the potential lifetime and annual costs of smoking, examining the annual cost of a cigarette pack per day to health care expenditures, income losses and other costs associated with smoking and exposure to secondhand smoke

Meanwhile, non-cigarette combustible tobacco consumption increased by 117.1% during that same period