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Studies have reported 1.7 to 4 times the level of acrylamide biomarkers in the urine and blood of smokers compared to non-smokers [17, 64], and there have been daily exposure extimates of 3 g/kg bw acrylamide uptake from cigarette smoking [65]

What can we learn from Japan

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The seventh president, Tennessean Andrew Jackson, was such a regular user of plug that brass spittoons--now in his Tennessee estate, the Hermitage--were installed at the White House