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Materials and methods Observational studies investigating the association between the synergistic consumption of alcohol and tobacco and OSCC occurrence were included

The most well-known representative is benzo[a]pyrene, classified by the IARC as a Group 1 carcinogen (IARC, 2023)

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A 2000 study published in the British Medical Journal found each cigarette took an average of 11 minutes of a person's life expectancy