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"When we ended our run on The Tonight Show and my professional life continued, whenever a big career decision needed to be made, I always got the OK from The Boss

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As is expected for any model, cell culture experiments inherently have factors that need to be considered for reproducibility, such as choosing the most appropriate cell type/line, passage of the cells, confluency of cells during treatment, serum deprivation, treatment dose, duration, and handling techniques

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