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Secondly, e-cigarettes also contain nicotine, which has been implicated in vasoconstriction in the eye and may increase the risk for glaucoma via vasoconstriction of episcleral veins or arteries supplying the optic nerve. While e-cigarette use is associated with increased prevalence of vision impairment, the authors suggest a longitudinal, observational study should be conducted to further investigate this association.

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