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Helps regulate metabolism at the genetic level

Sasaki et al., 2006, 2011

Cz prac raportowaa wyduenie mediany ycia oraz modulacj czstoci spontanicznych nowotworw w kohortach zwierzcych obserwacje te pochodz gwnie z jednego nurtu badawczego i wymagaj niezalenej replikacji

Among them, imidazole ketone erastin (IKE) had a stronger inhibitory effect and greater metabolic stability than erastin, which led IKE to be an excellent candidate for investigating ferroptosis initiation in vivo and in vitro (Hirschhorn and Stockwell 2019)

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44 Although cellular free iron concentrations are generally kept very low by binding to ferritin, iron can be mobilized from this binding protein by superoxide