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In an important study by Khokhar and Tyndale, the authors found that 7 days of nicotine treatment increased CYP2B expression in the brain, but not liver, and surprisingly, this change in metabolism was sufficient to potentiate the sleep-inducing effects of the general anesthetic propofol in male rats (167)

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In the 1930s, he took action, partnering with eyewear manufacturer Bausch & Lomb to develop sunglasses specifically for aviators like himself and his colleagues

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Relationship between fine particulate air pollution and ischaemic heart disease morbidity and mortality