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Four EDS variants (i.e., arthrochalasia, classic with vascular rupture, cardiac-valvular, and EDS/osteogenesis imperfecta overlap) are caused by dominant or recessive mutations in genes encoding the two chains of collagen type I ( COL1A1 and COL1A2 ) [2225]

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Persistent heavy smoking as risk factor for Major Depression (MD) incidence: Evidence from a longitudinal Canadian cohort of the National Population Health Survey