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In Women and Smoking Since 1890 (Routledge Series), social historian Rosemary Elliot writes, The social meaning of smoking was gendered, and that the act functioned as a visible delineator of gendered social space. In 1900, The Ladies Realm published a discussion titled Should Women Smoke? a question that itself signalled how unsettled the issue remained

The Tobacco Hazards Prevention Act () promulgated in 1997 required warning message to be printed on cigarette packages, but it had a limited effect, so the act was amended in 2007 to ensure that warning images and text cover at least 35 percent of the packaging, starting in 2009

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Over time, this leads to scarring inside the kidneys, reducing their filtering ability

-- E-cigarettes will face new regulations by the U.S