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Anxiety- and depression-like behaviors induced by adolescent nicotine exposure can be rescued in adult male rats by re-exposure to treatment with SSRIs [99], or, intriguingly, by re-exposure to nicotine

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While the exact mechanism underlying the protective effect of smoking remains unclear, potential mechanisms include immunomodulatory, vascular, and intestinal

Since both studies found similar results, both methods appear useful in investigating airborne nicotine levels in outdoor locations

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