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2019) discovered that hypoxia upregulates Cul7 expression in PASMCs and that siRNA-mediated knockdown of Cul7 significantly reduces P53 protein levels, alleviating excessive proliferation and migration of PASMCs induced by hypoxia

In contrast, almost all individual-level studies revealed a link between current vaping and future smoking among young people, but the researchers noted it was unclear whether there was a causal relationship