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217 In addition, a double-blind, placebo-controlled, crossover trial with 23 participants reported that taking 200 mg CoQ10 daily did not affect exercise performance or markers of exercise-induced oxidative stress in hemodialysis patients

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The mechanism is not fully understood but it is believed that the increased intracellular glutathione levels and increased ROS 217 are closely coupled with the build-up of toxic lipid peroxides and consequent ferroptosis