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Other Affiliation: Kaiser Permanente Northern California (KPNC), Division of Research, Oakland, CA, USA Tiwari, Hemant ORCID: Other Affiliation: Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA Turman, Constance ORCID: Other Affiliation: Department of Epidemiology, Harvard T.H

Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century

Arase Y, Suzuki F, Suzuki Y, Akuta N, Kobayashi M, Kawamura Y, Yatsuji H, Sezaki H, Hosaka T, Hirakawa M, et al

Dr Fernando Fernndez Bueno , head of the Spanish platform for tobacco harm reduction, takes a different view, arguing that the consultation process risks limiting the scientific debate on smoke-free products

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History [edit] The Duke Homestead was built about 1852 by Washington Duke, on a farm that was about 300 acres (120 ha) in size when the American Civil War broke out