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Because there is no burning flame, IQOS produces fewer combustion byproducts than cigarettes

however, the overall nicotine use in this age group has stayed relatively stable, hovering around 15-17%[2]

These seemingly conflicting nicotine results may be partly accounted for by the developmental stage in which it is consumed, with higher FA more commonly observed in younger nicotine users (Hudkins et al., 2012

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Flavor is known to influence uptake of smoke-free products and subsequent switching behavior among adult individuals who smoke [25, 35] and is also a topic of regulatory concern in the US for both combustible [36] and smoke-free tobacco and nicotine products [37]