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A realistic alternative is to encourage these smokers to switch to ECs, a much less harmful source of nicotine (Polosa et al ., 2013)

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Inhale slowly and deeply through your nose for four seconds, then exhale through pursed lips for four seconds

High-adrenaline concentrations induce vasoconstriction and increased cardiac contractility through activation of 1 adrenoreceptors and 1 adrenergic receptors, respectively [70], eventually leading to elevated blood pressure