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Many companies came up with nicotine supplementary products helping smokers to quit smoking or in managing nicotine dependency

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According to health authorities, tobacco use leads to higher healthcare costs, more sick days, and premature deathall of which far outweigh any short-term savings on tobacco purchases

An important step in atherogenesis is associated with the atherogenic modification of LDL, involving their oxidation, which makes LDL proinflammatory [158,168]