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Importantly, these changes are further elevated in lung cancers or pre-cancers (abnormal cells or tissue that have the potential to develop into cancer), when compared to the normal lung tissue, supporting the idea that the epigenetic changes associated with smoking allow cells to grow more quickly

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Continuing to smoke despite health issues means that someone persists in smoking tobacco or using tobacco products even when they are well aware of the adverse health consequences and are experiencing negative health effects as a direct result of their smoking habit

Louis Armstrong (1956)

Transboundary health impacts of transported global air pollution and international trade