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Conventional in vitro models frequently fall short in replicating the intricate lung microenvironment and the dynamic exposure conditions present in vivo, thereby reducing their predictive accuracy in preclinical studies 26,44

If you smoke 15 a day, youre consuming roughly 15 to 30mg of nicotine in total, though absorbed amounts vary by brand and smoking style

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Wertis L, Sugg MM, Runkle JD, Rao D

Berg CJ, Schauer GL, Buchanan TS, Sterling K, DeSisto C, Pinsker EA, et al