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It is not part of any FDA-approved drug formulation and has not been found safe or effective for any condition at this time

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Berberine improves cognitive impairment by simultaneously impacting cerebral blood flow and -Amyloid accumulation in an app/tau/ps1 mouse model of Alzheimers disease

Although AEs were reported more frequently in Caucasian subjects than in Japanese subjects, the overall frequencies of AEs were similar for apixaban- and placebo-treated subjects within each ethnic group and there were no observed dose-related AEs trends in either group