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This study was conducted in accordance with the ethical principles of the Declaration of Helsinki

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"We found that in Norway, 85 per cent of lung cancer cases among women could have been avoided if the women did not smoke, so more than eight out of ten cases", Selnes Hansen says

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Keywords: chronic obstructive pulmonary disease, glucose metabolism reprogramming, cigarette smoke, mitochondrial dysfunction, targeted metabolic intervention Introduction Chronic obstructive pulmonary disease (COPD) is a prevalent and heterogeneous respiratory disorder characterized by irreversible airflow limitation and chronic respiratory symptoms, with primary clinical phenotypes including chronic bronchitis and emphysema