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Shp2 plays a key role in acute cigarette smoke-induced lung inflammation, in which pulmonary epithelial knockout of Shp2 reduced IL-8 release and lung inflammation in CS-exposed mice [135]

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5 Paragraph 1 of Annex 1 of the TBT Agreement, supra note 3, defines a technical regulation as including a [d]ocument which lays down product characteristics

Generally yes but coverage limits and exclusions may apply

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