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We need to raise awareness of the symptoms, the risk factors, and most importantly, the importance of early detection. Richard Holliday is a senior lecturer and honorary consultant in restorative dentistry at Newcastle University

However, it can contribute to mild dehydration and noticeable dryness

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"Kids look at the toy, not at the packaging," he added

Heavy smokers (12.4 8.4 cigarettes per day, n = 11) have found that e-cigarettes, especially those from the 1st generation, were unsatisfactory because delivery of nicotine was ineffective as compared with conventional cigarettes 22

The review includes 24 peer-reviewed studies conducted over two decades, suggesting that packaging plays an important role in encouraging young people to try cigarettes