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How Nicotine Addiction Works in the Brain Upon inhalation, nicotine rushes to the brain within seconds, binding to receptors and triggering a flood of dopamine, the "feel-good" neurotransmitter

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(DOCX 22 kb) Rights and permissions Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

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doi: 10.1016/j.chest.2019.02.403 48 TangMElickerBMHenryTGieradaDSSchieblerMLHuangBKet al