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According to one study in 2015, one puff from a nicotine-free shisha pen contained enough propylene glycol and glycerol, two common base liquids, to cause mouth and throat irritation.[6] When vaporized, these substances may have the potential to form carcinogenic (cancer-causing) compounds

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Besides lung cancer, exposure to tobacco smoke can also provoke asthma-like symptoms, chronic bronchitis, irritation of the eyes and nose, and heart issues in dogs