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Nearly 9 out of 10 adults who smoke cigarettes daily first tried smoking by the age of 18 (CDC, 2024) Among past-month users of nicotine products, nearly two thirds of adolescents aged 12 to 17 (63.1%) vaped nicotine but did not use tobacco products (SAMHSA, 2022)

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Unbound lorazepam clearance normalized to body-weight was comparable in adolescents and adults

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