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If you have any diseases that mean your liver cells are damaged, smoking increases the severity of these damages

5 Why opening a window doesnt help Opening a window or restricting smoking to a specific room offers little protection against exposure to secondhand smoke

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158 In cancers, TGF- expression significantly increases with the increasing tumor grade, suggesting a close relationship between this cytokine and malignant tumor changes

Cold Spring Harb Perspect Biol 5:a012914 Jorgensen ED, Zhao H, Traganos F, Albino AP, Darzynkiewicz Z (2010) DNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco-and nicotine-free cigarettes