The mean maximal increase in heart rate was 14.1 bpm for UB cigarette, 8.5 bpm for nicotine gum, 13.2 bpm for Vuse Alto 2.4%, and 14.2 bpm for Vuse Alto 5%
With commercial RIP cigarettes becoming the dominant products available in most North America and Europe countries as demanded by regulations (Gann 2007
Possible implications These results signal the policy and research importance of understanding the phases of the tobacco epidemic, and the variation in mortality consequences from various trajectories of smoking prevalence
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