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Research has identified lethal doses as low as 713 mg/kg in children and 3060 mg for adults
The disparate results in different studies may have arisen from analytical challenges in measuring 8-oxodG without artifactual oxidation of normal dG during sample processing and analysis, high background levels of this lesion in cellular DNA, multi-source nature of 8-oxodG in biospecimens (endogenous and exogenous), different methodologies used, conditions and time of sample collection, inter- and intra-individual variations in subjects metabolic capacity, DNA repair activity, or antioxidant defenses, and various confounding factors [23, 138, 150, 151]
While the casual smoke exposure of a campfire or outdoor barbecue typically wont negatively affect your health, prolonged exposure to AQIs in the 100 range or higher can leave you coughing and wheezing, struggling to breathe with eyes stinging
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