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These toxic compounds in vivo can decrease endogenous antioxidants, increase lipid peroxidation and oxidative stress, and elevate pro-inflammatory factor concentrations in the blood of the host (van der Vaart et al., 2004

For example, gambling disorder is recognized in the Diagnostic and Statistical Manual of Mental Disorders as an addictive disorder

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Other side effects have been reported such as abdominal pain, constipation, abdominal distension, abnormal dreams, insomnia, dizziness, dry mouth, weight increase, increased appetite, and headache