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[137] Journalist Burt Boyar observed, "Sinatra had had it

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doi:10.3389/fnbeh.2017.00134 pmid:28790900 Lack CM, Jones SR, Roberts DC (2008) Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats

Two other prescription medications are available that do not contain nicotine

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