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These migratory DCs specifically penetrate the T-cell-rich paracortical zones and transmit a package of information consisting of processed antigen, along with costimulatory signals and secreted factors, that will program the ensuing T-cell response: tolerogenic, Th1, Th2, or Th17

[10] East K, Reid JL, Burkhalter R, Wackowski OA, Thrasher JF, Tattan-Birch H, Boudreau C, Bansal-Travers M, Liber AC, McNeill A, Hammond D

Public Health England has also stated that vaping is at least 95% less harmful than smoking traditional cigarettes, making it a much safer alternative for those trying to quit smoking

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