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Next, Horn reviewed the supposed advantages of the low-tar scheme against the background of what he said was a growing public conviction that cigarette smoking really was harmful to health, and pointed out that many smokers were adjusting their smoking habits accordingly

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Lung exposure to fine particulate matter, such as monosodium urate crystals, asbestos, and crystalline silica, results in persistent inflammation, mediated primarily by the NLRP3 inflammasome [72]

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