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Yamamoto GL, Aguena M, Gos M, Hung C, Pilch J, Fahiminiya S, et al

Disruption of this delicate microbial balance by cigarette smoke leads to persistent immune activation, epithelial injury, and heightened susceptibility to infection and chronic airway disease

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4(3) illustrated Zvolensky and Bernsteins (2005) integrative model relating smoking and panic disorder

During smoking, this complex biomass is subjected to high temperatures and varying oxygen concentrations, producing an incomplete combustion that generates more than 7,000 toxic compounds