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Here we review the immunosuppressive effects of cigarette smoke and the mechanisms by which smoking affects host innate immunity including structural and functional changes in the respiratory ciliary epithelium, lung surfactant protein, and immune cells such as alveolar macrophages, neutrophils, lymphocytes and natural killer (NK) cells

National Alliance on Mental Illness (NAMI)

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As a result, smokers tend to increase the amount of tobacco to obtain the pleasurable effects (19)

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