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"Development and validation of betel-year: a clinical tool for quantifying exposure to betel quid chewing, utilizing nuclear morphometric analysis and validated by cytomorphological analysis"

HARMS OF DETECTION AND EARLY TREATMENT The USPSTF found inadequate evidence on the harms of screening

13 There is some evidence of specificity in the factors predicting smoking among adolescents at different smoking stages (such as people who do not smoke, people who experiment with smokingand people who smoke regularly), with peer smoking and low school connectedness found to be more influential in later stages of smoking than in early stages, and alcohol use thought to be more influential in early stages

Nicotine is addictive, so the first days and weeks can be tough with intense cravings, irritability, and trouble focusing

PMID: 39507882

Its market share in Japan has rapidly increased from less than 1% in the beginning to 16.9% as of the first quarter of 2019