First, the tax base is exceedingly narrow and is thus likely to result in volatile revenue
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Nicotine crosses the placental barrier resulting in a neuroteratogenic effect in the developing fetus
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These 10 studies are summarized narratively because sales/purchases and prevalence/frequency/other outcomes are not appropriate for direct comparison, even in a random-effects model, and because each combination of outcome (current use, daily use) and population (adults, adolescents) had too few results for separate model-based meta-analyses
In its Technical Project Lead (TPL) summary review of the decision, the FDA determined that the evidence that has been submitted by PMI did not support issuing risk modification orders at this timeaccording to the FDA's interpretation of the Tobacco Control Act standard for issuance of such ordersbut that the evidence submitted did support issuing exposure modification orders for these products