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Tolerance and Dependence Prolonged misuse of gabapentin can lead to the development of tolerance, where you require higher doses to achieve the same effects, and dependence, which can result in addiction and withdrawal symptoms when you stop using

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Bibcode:2005JMedC..48.3474C

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However, we have not been able to do this for all respondents, particularly in recent years, and consequently are not able to make use of the entire BRFSS dataset in this analysis

TUDGP (Tobacco Use and Dependence Guideline Panel)