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Human DSIP Research for Chronic Insomnia The historical studies reported mixed findings and did not meet modern confirmatory-trial standards

DOI: 10.1016/j.pharmther.2020.02.014

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Zinc, an anti-inflammatory antioxidant, which is required for the biological activity of thymulin, reduced the secretion of IL-1 beta (IC(50) = 62 microM), TNF-alpha (IC(50) = 1000 microM), and, to a lesser extent, IL-6