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In addition, we required that strongly heterogeneous variants had an MDS component effect that was significantly different from zero and were polymorphic in two or more ancestry-stratified cohorts to ease interpretation of heterogeneous effects

Unlike the Spanish colonies in the Caribbean islands, Native Americans were not enslaved in Virginia to provide the initial labor force

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Bias Steps to reduce bias were done by anonymizing responses, using a validated tool, and excluding individuals with known comorbidities that might complicate the results

Below is a clear comparison of common nicotine products, how much they typically contain, and how much is actually absorbed

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