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26,27 However, even when these combustion by-products are removed, as in nicotine-only products, CV toxicity largely persists, because nicotine itself is harmful, 8,9 E-cigarettes: less harmful, not harmless E-cigarettes have often been marketed as harm reduction tools
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E-cigarette use has been shown to alter the airway epithelium (142, 143)(Table 9), including a large body of proteomic, metabolomic, and transcriptomic data
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