Other systemic toxicity A PMI study found that IQOS does not inhibit monoamine oxidase, which are enzymes suggested to be involved in smoking addiction, due to the reduced emission of possible monoamine oxidase inhibitors like acetaldehyde and 2-naphthylamine 30
While exposure to secondhand smoke is a known cancer risk, its mutational effect was far less pronounced than that seen with air pollution
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We included multiple observations from a single study when effects were reported by location or source of exposure and/or separately by sex or other subgroups
These results corroborate those of previous studies, some of which were performed by the manufacturer of IQOS, the cigarette manufacturer Philip Morris International (PMI)
