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Nair U, Obe G, Nair J, Maru GB, Bhide SV, Pieper R, et al Evaluation of frequency of micronucleated oral mucosa cells as a marker for genotoxic damage in chewers of betel quid with or without tobacco Mutat Res

In a landmark study in 1950 examining the effect of tobacco smoking on the occurrence of lung cancer, Doll and Hill used smoking exposure metrics of cigarettes smoked in lifetime, age of starting smoking, and cigarettes per day (6)

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