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As the study did not involve primary data collection, randomization and blinding, data exclusions were not relevant to the present study, and, as such, no data were excluded and we performed no randomization or blinding

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Methods Cell culture Beas-2B cells and A549 cells, human lung epithelial cells, and p53-deficient H1299 lung cancer cells were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA) and maintained in DMEM (Thermo Fisher, Waltham, MA, USA) containing 10% fetal bovine serum (FBS, HyClone, Logan, UT, USA) and antibiotics (Invitrogen, Carlsbad, CA, USA)

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