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Ethics statement The studies involving human participants were reviewed and approved by Fundao de Medicina Tropical Doutor Heitor Viera Dourado (FMT-HVD) ethical board committee (CAAE: 50812815.0.0000.0005, approval number 1.358.054) Fundao Hospitalar de Hematologia e Hemoterapia do Amazonas (CAEE: 51257921.2.0000.0009, approval number #4.982.395/2021)

This antagonistic effect of polyphenols has been previously observed by Lui et al